{"id":4191,"date":"2014-10-01T01:07:41","date_gmt":"2014-10-01T01:07:41","guid":{"rendered":"http:\/\/lafeber.com\/staging\/vet\/?p=4191"},"modified":"2025-11-18T18:09:52","modified_gmt":"2025-11-19T00:09:52","slug":"basic-information-for-guinea-pigs","status":"publish","type":"post","link":"https:\/\/lafeber.com\/vet\/basic-information-for-guinea-pigs\/","title":{"rendered":"Basic Information Sheet:  Guinea Pig"},"content":{"rendered":"<h1>Guinea Pig (<em>Cavia porcellus<\/em>)<\/h1>\n<p><a href=\"https:\/\/lafeber.com\/vet\/wp-content\/uploads\/Guinea-Pig-by-Johan-Larsson-cropped-labeled.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-8370\" src=\"https:\/\/lafeber.com\/vet\/wp-content\/uploads\/Guinea-Pig-by-Johan-Larsson-cropped-labeled.jpg\" alt=\"guinea pigs\" width=\"600\" height=\"336\" srcset=\"https:\/\/lafeber.com\/vet\/wp-content\/uploads\/Guinea-Pig-by-Johan-Larsson-cropped-labeled.jpg 700w, https:\/\/lafeber.com\/vet\/wp-content\/uploads\/Guinea-Pig-by-Johan-Larsson-cropped-labeled-500x280.jpg 500w, https:\/\/lafeber.com\/vet\/wp-content\/uploads\/Guinea-Pig-by-Johan-Larsson-cropped-labeled-400x224.jpg 400w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<div class=\"ezcol ezcol-one-third\">\n<h2>Natural history<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><br \/>\nThe guinea pig is a native of Peru, Brazil, and Argentina that was domesticated by the Inca Indians. Guinea pigs are also known as &#8220;cavies&#8221;, a term derived from the South American vernacular. Male guinea pigs are called &#8220;boars&#8221; and females are &#8220;sows&#8221;.<\/p>\n<p><\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2>Taxonomy<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><br \/>\n<strong>Class<\/strong>: <em>Mammalia<\/em><\/p>\n<p style=\"padding-left: 30px;\"><strong>Order<\/strong>: <em>Rodentia<\/em><\/p>\n<p style=\"padding-left: 60px;\"><strong>Suborder<\/strong>: <em>Hystricomorpha<\/em><\/p>\n<p style=\"padding-left: 90px;\"><strong>Family<\/strong>: <em>Caviidae<\/em><\/p>\n<p><\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2>Breeds<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><br \/>\nOver 20 <a title=\"Guinea Pig Breeds\" href=\"https:\/\/lafeber.com\/vet\/guinea-pig-breeds\/\">breeds<\/a> of guinea pig are recognized with the three most popular being:<\/p>\n<table>\n<tbody>\n<tr>\n<td>Peruvian:<\/td>\n<td>Long hair<\/td>\n<\/tr>\n<tr>\n<td>American or English:<\/td>\n<td>Short hair<\/td>\n<\/tr>\n<tr>\n<td>Abyssinian:<\/td>\n<td>Whorled or rough hair<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2>Diet<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><br \/>\nGuinea pigs are <a href=\"https:\/\/lafeber.com\/vet\/how-to-feed-the-small-herbivore-gastrointestinal-tract\/\" rel=\"noopener\">strict herbivores<\/a>. A sound diet consists of <a href=\"https:\/\/lafeber.com\/vet\/hay-feeding-small-herbivores\/\">high-quality hay<\/a>, fresh foods, and water. Offer unlimited grass hay, as guinea pigs eat small portions throughout the day. Alfalfa or clover hay should only be given to juvenile animals as the high calcium content can predispose adults to renal calcification. Fresh food can consist of grasses, herbs, leafy greens, peppers, and other vegetables. Avoid or limit fruits in the diet. Too many simple carbohydrates can lead to diarrhea and\/or dysbiosis.<\/p>\n<p>Guinea pigs of all ages require a dietary source of <a href=\"https:\/\/lafeber.com\/vet\/vitamin-c-content-of-selected-foods\/\">vitamin C<\/a> (10-30 mg\/kg per day). Fresh foods rich in vitamin C can provide sufficient levels of this nutrient. Additionally, commercial guinea pig pellets often contain vitamin C and small amounts of pellets (about \u00bc cup a day) can be offered alongside hay and fresh food. Pellets should be fresh and relatively high in fiber, low in sugars and calcium, and grain free. The stability of vitamin C decreases over time and the vitamin C content of pellets is also reduced by exposure to dampness, heat, and light.<br \/>\n<\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2>Husbandry<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><\/p>\n<table>\n<tbody>\n<tr>\n<td>\n<ul>\n<li>Guinea pigs are <a href=\"https:\/\/lafeber.com\/vet\/behavior-basics-guinea-pig\/#Activity\">crepuscular<\/a>.<\/li>\n<li><a href=\"https:\/\/lafeber.com\/vet\/behavior-basics-guinea-pig\/#Husbandry-related_behavior\" target=\"_blank\" rel=\"noopener\">Caging<\/a> should be well ventilated with solid flooring. Be sure to provide visual security in the form of a hide box (one hide box per animal).<\/li>\n<li>The enclosure size for two guinea pigs should be at least 120 x 60 x 50 cm or 50 x 24 x 20 (length x width x height). Increase the base area by at least 20% for each additional pig is necessary (1 m2 or 10 sq ft per animal is ideal).<\/li>\n<li>Clean and change <a href=\"https:\/\/lafeber.com\/vet\/behavior-basics-guinea-pig\/#water\">water bottles<\/a> frequently.<\/li>\n<li>Clinically normal rabbits harbor a variety of bacterial organisms that can cause death and disease in guinea pigs. Never house guinea pigs and other rodents near rabbits.<\/li>\n<li>Guinea pigs are <a href=\"https:\/\/lafeber.com\/vet\/behavior-basics-guinea-pig\/#Social_behavior\" target=\"_blank\" rel=\"noopener\">highly social animals<\/a> that should never be housed alone. Pairs, trios, harems (1 boar and 1-10 sows) as well as single-sex groups can life together peacefully.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2>Normal physiologic values<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><\/p>\n<p>&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td>Temperature<\/td>\n<td>37.2-38.6\u00baC<\/td>\n<td>99-101.5\u00baF<\/td>\n<\/tr>\n<tr>\n<td>Pulse<\/td>\n<td>230-380 bpm<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Respiration<\/td>\n<td>40-100 bpm<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Body weight<\/td>\n<td>Adult male<\/td>\n<td>900-1200 g<\/td>\n<\/tr>\n<tr>\n<td><\/td>\n<td>Adult female<\/td>\n<td>700-900 g<\/td>\n<\/tr>\n<tr>\n<td>Mean life span<\/td>\n<td>6-8 y<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/lafeber.com\/vet\/guinea-pig-reproduction-basics\/\">Sexual maturity<\/a><\/td>\n<td>2-4 months<br \/>\nMales will exhibit mounting behavior as early as 1 month of age.<br \/>\nFemales can become pregnant as early as 4-5 weeks of age.<\/td>\n<td>2 months (F)<br \/>\n3 months (M)<\/td>\n<\/tr>\n<tr>\n<td>Breeding maturity<\/td>\n<td>Male:\u00a0 3-4 months<br \/>\nFemale:\u00a0 6-8 months<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Estrous cycle<\/td>\n<td>16-17 d, polyestrous<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/lafeber.com\/vet\/guinea-pig-reproduction-basics\/#Gestation\">Gestation<\/a><\/td>\n<td>59-72 days (average 68 days)<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Birth weight<\/td>\n<td>45-115 g (inversely related to litter size)<br \/>\n70-100 g<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Litter size<\/td>\n<td>1 to 13 (2 to 4 is the usual)<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/lafeber.com\/vet\/guinea-pig-reproduction-basics\/#Weaning\">Weaning age<\/a><\/td>\n<td>21 days (180 g)<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Target environmental temperature:<\/td>\n<td>18-26\u00baC<br \/>\nAvoid temperatures above 28\u00b0C (82\u00b0F)<\/td>\n<td>65-79\u00baF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2>Anatomy \/ physiology<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><\/p>\n<table>\n<tbody>\n<tr>\n<td>Musculoskeletal:<\/td>\n<td>Rodents have a distinctive masseter muscle. The zygomatic arch of the skull and the dental anatomy is related to their feeding habits.<\/p>\n<p>Females must be bred before 6-9 months of age. Immature male s and females have a fibrocartilaginous pelvic symphysis fusion which becomes ossified over 1 year of age. The symphysis remains cartilaginous in<a href=\"https:\/\/lafeber.com\/vet\/guinea-pig-reproduction-basics\/#Parturition\"> primiparous sows<\/a> so the pelvic canal can dilate allowing passage of the large fetus.<\/td>\n<\/tr>\n<tr>\n<td><a title=\"Dental Anatomy of Rabbits and Rodents\" href=\"https:\/\/lafeber.com\/vet\/dental-anatomy-of-rabbits-and-rodents\/\">Dental formula<\/a>:<\/td>\n<td>I 1\/1\u00a0 \u00a0C 0\/0\u00a0 \u00a0PM 1\/1\u00a0 \u00a0M 3\/3<\/p>\n<p>All teeth are open-rooted and show lifelong growth.<\/p>\n<p>The lower incisors are normally 3X longer than the upper incisors.<\/td>\n<\/tr>\n<tr>\n<td>Special Senses:<\/td>\n<td>Large ears with thin-walled pinnae and well-developed bullae.<\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/lafeber.com\/vet\/guinea-pig-reproduction-basics\/\">Urogenital<\/a>:<\/td>\n<td>Males have lateral scrotal swellings on each side of the anus.<\/p>\n<p><a href=\"https:\/\/lafeber.com\/vet\/guinea-pig-reproduction-basics\/#glands\">Accessory glands<\/a> include a prostate, coagulating gland, bulbourethral gland, and seminal vesicles. Seminal vesicles are large, yellow-white tubular structures which lie dorsal to the bladder. The seminal vesicles can be confused with the uterus.<\/td>\n<\/tr>\n<tr>\n<td>Respiratory:<\/td>\n<td>All rodents are obligate nasal breathers.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2>Restraint<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><br \/>\nMost pet guinea pigs are calm, gentle animals that rarely bite. <a href=\"https:\/\/lafeber.com\/vet\/behavior-basics-clinical-approach-guinea-pig\/#Handling_and_restraint\">To pick up a guinea pig<\/a>, cup one hand gently under the thorax and use the other hand to support the hind end. Hold the rump lower than the rest of the body.<br \/>\n<\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2><a title=\"Venipuncture in Small Mammals\" href=\"https:\/\/lafeber.com\/vet\/venipuncture-in-small-mammals\/\">Venipuncture<\/a><\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><br \/>\nLarge volumes:\u00a0 <a href=\"https:\/\/lafeber.com\/vet\/venipuncture-in-small-mammals\/#Jugular_vein\">Jugular vein<\/a>, <a href=\"https:\/\/lafeber.com\/vet\/venipuncture-in-small-mammals\/#Cranial_vena_cava\">cranial vena cav<\/a>a (only under sedation\/anesthesia)<br \/>\nSmall volumes:\u00a0 <a href=\"https:\/\/lafeber.com\/vet\/venipuncture-in-small-mammals\/#Cephalic_vein\">Cephalic vein<\/a> or <a href=\"https:\/\/lafeber.com\/vet\/venipuncture-in-small-mammals\/#Saphenous_vein\">lateral saphenous vein<\/a><br \/>\n<\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2>Fluid therapy<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><br \/>\nAdminister warm fluids: 38-39\u00b0C (100-102\u00b0F).<\/p>\n<p>Maintenance fluids are estimated as 50-75 ml\/kg\/day.<\/p>\n<ul>\n<li>Dehydration (%) x BW (kg) x 1000 ml\/L = fluid deficit (ml)<\/li>\n<li>Correct fluid deficits over 12-24 hours<\/li>\n<\/ul>\n<p>Subcutaneous (SC) fluids are indicated only for animals with a stable circulatory system and mild dehydration (max 5%).<\/p>\n<ul>\n<li>Administer SC fluids up to three times per day (give one-third of calculated fluid volume at a time)<\/li>\n<li>Infuse up to 150 ml\/kg\/day (average 40-60 ml\/kg)<\/li>\n<\/ul>\n<p>Intravenous or intraosseous fluid therapy is indicated in critical patients. <a href=\"https:\/\/lafeber.com\/vet\/intravenous-catheter-placement-in-small-mammals\/\">Intravenous (IV) catheters<\/a> are placed with growing frequency in guinea pigs, but when IV catheterization fails or when veins are too small or too fragile, an <a href=\"https:\/\/lafeber.com\/vet\/how-to-guide-intraosseous-catheter-placement-in-small-mammals\/\">intraosseous or IO catheter <\/a>can be an excellent option.<\/p>\n<table>\n<tbody>\n<tr>\n<th>Catheter type<\/th>\n<th>Recommended sites<\/th>\n<th>Comments<\/th>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/lafeber.com\/vet\/intravenous-catheter-placement-in-small-mammals\/\" target=\"_blank\" rel=\"noopener\">Intravenous catheter<\/a><\/td>\n<td>Cephalic or lateral saphenous vein<\/td>\n<td>Slow bolus: 5-10 ml\/kg IV every 8 hours<\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/lafeber.com\/vet\/how-to-guide-intraosseous-catheter-placement-in-small-mammals\/\">Intraosseus catheter<\/a><\/td>\n<td>Proximal humerus, proximal tibia, proximal femur<\/td>\n<td>20-22 gauge (1-1.5 inch) spinal needle<br \/>\nLocal anesthesia with lidocaine<br \/>\nUse survey radiographs to confirm placement<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2>Important medical conditions<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><\/p>\n<p><!--\n \t\n\n<li><a title=\"Dystocia in Guinea Pigs\" href=\"https:\/\/lafeber.com\/vet\/dystocia-in-guinea-pigs\/\">Dystocia<\/a><\/li>\n\n\n--><\/p>\n<ul>\n<li>Bacterial pneumonia<\/li>\n<li><a href=\"https:\/\/lafeber.com\/vet\/guinea-pig-reproduction-basics\/#dystocia\">Dystocia<\/a><\/li>\n<li><a title=\"Mange in Exotic Small Mammals\" href=\"https:\/\/lafeber.com\/vet\/mange-in-exotic-small-mammals\/\" rel=\"noopener\">Fur mites<\/a><\/li>\n<li>Hypovitaminosis C or scurvy (can reportedly occur within 4 days of dietary decrease)<\/li>\n<li><a title=\"Dental Disease in Rabbits and Rodents\" href=\"https:\/\/lafeber.com\/vet\/rabbit-and-large-herbivorous-rodent-dental-disease\/\">Malocclusion<\/a><\/li>\n<li><a href=\"https:\/\/lafeber.com\/vet\/guinea-pig-reproduction-basics\/#cysts\">Ovarian cysts<\/a><\/li>\n<li>Pododermatitis<\/li>\n<li><a href=\"https:\/\/lafeber.com\/vet\/guinea-pig-reproduction-basics\/#toxemia\">Pregnancy toxemia<\/a>, preeclampsia<\/li>\n<\/ul>\n<p><\/div><div class=\"ezcol-divider\"><\/div><br \/>\n<div class=\"ezcol ezcol-one-third\"><\/p>\n<h2>Antibiotics to avoid<\/h2>\n<p><\/div><br \/>\n<div class=\"ezcol ezcol-two-third ezcol-last\"><br \/>\n<a title=\"Antimicrobial Therapy and Dysbiosis in Rabbits\" href=\"https:\/\/lafeber.com\/vet\/antimicrobial-therapy-and-dysbiosis-in-rabbits-and-rodents\/\">Avoid antimicrobials<\/a> that attack only gram-positive bacteria such as beta-lactams.<br \/>\nP.L.A.C.E.:<\/p>\n<ul>\n<li>Penicillin<\/li>\n<li>Lincosamide, lincomycin<\/li>\n<li>Amoxicillin, ampicillin<\/li>\n<li>Cephalosporins, clindamycin<\/li>\n<li>Erythromycin<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><\/div><div class=\"ezcol-divider\"><\/div><\/p>\n<p>&nbsp;<\/p>\n<h2 class=\"ref\">References<\/h2>\n","protected":false},"excerpt":{"rendered":"<p>The guinea pig is a native of Peru, Brazil, and Argentina that was domesticated by the Inca Indians. This Basic Information Sheet reviews a variety of topics including natural history, breeds, diet, caging, normal physiologic values, anatomy\/physiology, restraint, venipuncture, important medical conditions, as well as antibiotics to avoid.<\/p>\n","protected":false},"author":5,"featured_media":8401,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[514,256,389,702],"class_list":["post-4191","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-breeds","tag-herbivore","tag-natural-history","tag-species-taxonomy","content_types-information-sheet","topics-anatomy-physiology","topics-husbandry","procedures-examination-evaluation","species-guinea-pig","species-mammals","species-rodent","channel-resources-education","contributor-pollock"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Basic Information Sheet: Guinea Pig - LafeberVet<\/title>\n<meta name=\"description\" content=\"The guinea pig is a native of Peru, Brazil, and Argentina that was domesticated by the Inca Indians. 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