Hyperadrenocorticism is a common and complex clinical condition in the pet ferret. This disease occurs most frequently in ferrets three years or older but has been reported in animals as young as one year of age. Presumptive diagnosis of adrenal disease in the ferret is based on history, clinical signs, imaging diagnostics, and steroid hormone analysis. While surgical therapy is the treatment of choice, palliative medical management typically relies on use of the GnRH analogs, leuprolide acetate or deslorelin.
Although the medical approach to anemia is the same as in dogs & cats, some red cell parameters and some differentials differ in the ferret.
The ferret with moderate to severe anemia will exhibit pallor of the mucous membranes, nasal planum and skin. If a clotting disorder exists, petechial, ecchymotic and purpural hemorrhages can also be observed. The owner may complain of lethargy and reduced activity.