Article  Case Study 

AEMV-Lafeber Case Report: Pituitary-Dependent Hyperadrenocorticism and Cholangiohepatitis in a Guinea Pig

A 3-year old intact male guinea pig was presented on emergency for suspected bloat and with a history of chronic hair loss. Clinical examination revealed non-pruritic symmetric truncal alopecia, thin skin, severe cachexia, and an abdominal fluid wave. Alkaline phosphatase, alanine transaminase, aspartate aminotransferase, gamma-glutamyl transferase, leukocytes (neutrophils), bilirubin, and serum cortisol were markedly elevated. Abdominal ultrasonography revealed peritoneal effusion, cholestasis, and cholelithiasis. Hyperadrenocorticism was diagnosed based on…

Article 

Adrenocortical Disease in Ferrets

Hyperadrenocorticism is a common and complex clinical condition in the pet ferret. This disease occurs most frequently in ferrets three years or older but has been reported in animals as young as one year of age. Presumptive diagnosis of adrenal disease in the ferret is based on history, clinical signs, imaging diagnostics, and steroid hormone analysis. While surgical therapy is the treatment of choice, palliative medical management typically relies on use of the GnRH analogs, leuprolide acetate or deslorelin.