The avian patient poses special challenges for delivery of injectable medications. Although the techniques involved are not unique to birds, special knowledge of avian anatomy as well as delicate, proficient technical skills are required. Depending on the species, the individual, and the clinical situation, injections can be delivered by intramuscular, intravenous, intraosseous, subcutaneous, intratracheal, or intracoelomic routes. Parenteral drug administration provides the advantage of delivering a precise dose when a rapid therapeutic response is necessary. Disadvantages include stress as well as the potential irritation or pathology that can occur at the injection site.