Two guinea pigs suspected of having hyperthyroidism based on weight loss, presence of a cervical mass, and elevated total thyroxine (TT4) levels were confirmed to have active thyroid masses via scintigraphy with Technetium-99 and treated with radioactive iodine therapy (I¹³¹). Both patients responded initially with weight gain and a decrease in the TT4. The purpose of this case series is to describe the use of scintigraphy to aid in confirming a diagnosis of hyperthyroidism, as well as to show the benefits and effectiveness of using radioactive iodine therapy (I¹³¹) to treat hyperthyroidism in guinea pigs in order to provide the best treatment protocol.
In humans and small animals, the combination of feeding reduced calorie foods, providing regular exercise and using behavior modification to change eating patterns bring about the best chance of achieving and maintaining weight loss (Toll 2010). A key nutritional factor for weight loss and the prevention of weight gain is to feed calorie-restricted diets.