A Refresher on Guinea Pig Medicine

View this RACE-approved webinar recording presented by Grayson Doss, DVM, DACZM. Guinea pigs are social, herbivorous rodents that are both a popular pet and laboratory animal throughout the world. This presentation reviews the basics of captive husbandry and clinical anatomy, as well as clinical techniques, including restraint, physical examination, venipuncture, radiography, and antibiotic therapy. Two common conditions, hypovitaminosis C and urolithiasis, are also explored . . .


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References

Álvarez ER, Solé LV, de Carellán Mateo AG. Comparison of subcutaneous sedation with alfaxalone or alfaxalone-midazolam in pet guinea pigs (Cavia porcellus) of three different age groups. J Am Vet Med Assoc. 2022;260(9):1024-1030. doi: 10.2460/javma.21.02.0104. PMID: 35333744.

Azevedo S, O’Malley B, Greene C, et al. Lower urinary tract diseases in guinea pigs: A 14-year retrospective study (2004-2018). Animals (Basel). 2022;13(1):112. doi: 10.3390/ani13010112. PMID: 36611721; PMCID: PMC9817880.

Behrens KN, Cray MT, Noonan B. Risk factors, complications, and outcomes of cystotomy in guinea pigs: 25 cases (2010-2023). J Am Vet Med Assoc. 2024;263(2):178-183. doi: 10.2460/javma.24.08.0558. PMID: 39476486.

Dadah HJ, Hawkins MG, Munk AW, et al. Risk and protective factors associated with clinical urolithiasis in pet guinea pigs (Cavia porcellus). J Exotic Pet Med 54:28-34. doi:  10.1053/j.jepm.2025.07.005.

Doss GA. Proximal jugular venipuncture in African pygmy hedgehogs (Atelerix albiventris). J Exotic Pet Med. 35: 94-96. doi: 10.1053/j.jepm.2020.08.013

Edell AS, Vella DG, Sheen JC, et al. Retrospective analysis of risk factors, clinical features, and prognostic indicators for urolithiasis in guinea pigs: 158 cases (2009-2019). J Am Vet Med Assoc. 2022;260(S2):S95-S100. doi: 10.2460/javma.21.09.0421. PMID: 35333752.

Levy IH, Di Girolamo N, Keller KA. Rectal temperature is a prognostic indicator in client-owned guinea pigs. J Small Anim Pract. 2021;62(10):861-865. doi: 10.1111/jsap.13388. Epub 2021 Jun 21. PMID: 34155652.

Moeremans I, Devreese M, De Baere S, Croubels S, Hermans K. Pharmacokinetics and absolute oral bioavailability of meloxicam in guinea pigs (Cavia porcellus). Vet Anaesth Analg. 2019;46(4):548-555. doi: 10.1016/j.vaa.2018.11.011. Epub 2019 Mar 23. PMID: 31153785.

Personett AR, Santangelo KS, Kendall LV, Sadar MJ. Hematologic parameters and blood cultures from the gingival vein compared with the cranial vena cava in guinea pigs. J Am Assoc Lab Anim Sci. 2019;58(6):817-822. doi: 10.30802/AALAS-JAALAS-19-000039. Epub 2019 Oct 29. PMID: 31662155; PMCID: PMC6926395.

Rodrigues MV, de Castro SO, de Albuquerque CZ, Mattaraia VGM, Santoro ML. The gingival vein as a minimally traumatic site for multiple blood sampling in guinea pigs and hamsters. PLoS One. 2017;12(5):e0177967. doi: 10.1371/journal.pone.0177967. PMID: 28531179; PMCID: PMC5439950.

Souza AR, Ozawa SM, Sadar MJ, et al. Clinical value of amylase and its prognostic accuracy in guinea pigs (Cavia porcellus). J Small Anim Pract. 2025;66(6):382-388. doi: 10.1111/jsap.13843. Epub 2025 Feb 25. PMID: 39995272; PMCID: PMC12167696.

Thompson Lewis T, Lennox AM. Nonsurgical removal of urethral uroliths using a self-retaining retractor with elastic stays in female guinea pigs (Cavia porcellus): 16 Cases (2006–2019). J Exotic Pet Med. 2021;36:11-15. doi: 10.1053/j.jepm.2020.09.006.

To cite this page:

Doss G. A refresher on guinea pig medicine. October 2, 2025. LafeberVet web site. Avaialble at https://lafeber.com/vet/guinea-pig-medicine/