AEMV-Lafeber Case Report: Hyperthyroidism Treated with Radiation Therapy (I-131) in Two Guinea Pigs

Key Points

  • This case report earned Honorable Mention in the 2018 AEMV Lafeber Company Student Case Report Contest.
  • Two guinea pigs suspected of having hyperthyroidism based on weight loss, presence of a cervical mass, and elevated total thyroxine levels were confirmed to have active thyroid masses via scintigraphy with Technetium-99 and treated with radioactive iodine therapy (I131).
  • Both patients responded initially with weight gain and a decrease in the total thyroxine.
  • This case series describes the use of scintigraphy to aid in confirming a diagnosis of hyperthyroidism, as well as to show the benefits and effectiveness of using radioactive iodine therapy (I¹³¹) to treat hyperthyroidism in guinea pigs in order to provide the best treatment protocol.

Two guinea pigs suspected of having hyperthyroidism based on weight loss, presence of a cervical mass, and elevated total thyroxine (TT4) levels were confirmed to have active thyroid masses via scintigraphy with Technetium-99 and treated with radioactive iodine therapy (I¹³¹). Both patients responded initially with weight gain and a decrease in the TT4. The purpose of this case series is to describe the use of scintigraphy to aid in confirming a diagnosis of hyperthyroidism, as well as to show the benefits and effectiveness of using radioactive iodine therapy (I¹³¹) to treat hyperthyroidism in guinea pigs in order to provide . . .


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References


1. Brandão J, Vergneau-Grosset C, Mayer J. Hyperthyroidism and hyperparathyroidism in guinea pigs (Cavia porcellus). Vet Clin North Am: Exot Anim Pract 16(2):407-420,2013.

2. Gibbons PM, Garner MM, Kiupel M. Morphological and immunohistochemical characterization of spontaneous thyroid gland neoplasms in guinea pigs (Cavia porcellus). Vet Path 50(2):334-342, 2013.

3. Hocker SE, Eshar D, Wounda RM. Rodent oncology: Diseases, diagnostics, and therapeutics. Vet Clin North Am Exot Anim Pract 20(1):111-134, 2017.

4. Künzel F, Hierimeier B, Christian M, et al. Hyperthyroidism in four guinea pigs: Clinical manifestations, diagnosis, and treatment. J Small Anim Pract 54(12):667-671, 2013.

5. Künzel F, Mayer J. Endocrine tumors in the guinea pig. Vet J 206(3):268-274, 2015.

6. Mayer J, Wagner R, Taeymans O. Advanced diagnostic approaches and current management of thyroid pathologies in guinea pigs. Vet Clin North Am Exot Anim Pract 13(3):509-523, 2010.

7. Müller K, Müller E, Klein R, et al. Serum thyroxin concentrations in clinically healthy pet guinea pigs (Cavia porcellus). Vet Clin Pathol 38(4):507-510, 2009.

8. Thorson L. Thyroid diseases in rodent species. Vet Clin No Am Exot Anim Pract 17(1):51-67, 2014.

To cite this page:

Frey T, Greenacre C. Hyperthyroidism treated with radiation therapy (I-131) in two guinea pigs. May 30, 2018. LafeberVet Web site. Available at https://lafeber.com/vet/hyperthyroidism-gpigs/