Zoonotic concern: Encephalitozoonosis in European Rabbits

Key Points

  • Many rabbits are asymptomatic carriers of E. cuniculi.
  • Encephalitozoon may be spread through contact with rabbit urine.
  • The immunocompromised are at risk for encephalitozoonosis.
  • Clinical disease in humans varies.
  • Avoid contact with the urine of infected or health rabbits, and always utilized good sanitation practices.

Encephalitozoon cuniculi is an obligatory intracellular microsporidian parasite that can infect a wide range of mammals, including humans. The primary host for E. cuniculi is the rabbit. Infections in rabbits are typically subclinical . . .

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Anane S, Attouchi H. Microsporidiosis: epidemiology, clinical data and therapy. Gastroentenrol Clin Biol 34(8-9):450-464, 2010.

Didler ES, Didler PJ, Snowden KF, Shadduck JA. Microsporidiosis in mammals. Microbes Infect 2(6):709-720, 2000.

Fournier S, Liguory O, Sarfati C, et al. Disseminated infection due to Encephalitozoon cuniculi in a patient with AIDS: case report and review. HIV Med 1(3):155-161, 2000.

Friedman E, Son H. The human-companion animal bond: how humans benefit. Vet Clin North Am Small Anim Pract 39(2):293-326, 2009.

Khan IA, Moretto M, Weiss LM. Immune response to Encephalitozoon cuniculi infection. Microbes Infect 3(5):401-405, 2001.

Kodjikian L, Garweg JG, Nguyen M, et al. Intraocular microsporidiosis due to Encephalitozoon cuniculi in a patient with idiopathic CD4+ T-lymphocytopenia. Int J Med Microbiol 294(8):529-533, 2005.

Künzel F, Joachim A. Encephalitzoonosis in rabbits. Parasitol Res 106(2):299-309, 2010.

Mathis A, Weber R, Deplazes P. Zoonotic potential of the microsporidia. Clin Microbiol Rev 18(3):423-445, 2005.

Mitchell MA, Tully TN. Zoonotic diseases. In: Quesenberry KE, Carpenter JW (eds). Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 2nd ed. Philadelphia; WB Saunders; 2003. P. 433.

Ozkan O, Ozkan AT, Zafer K. Encephalitozoonosis in New Zealand rabbits and potential transmission risk. Vet Parasitol 179(1-3):234-237, 2011.

Van Gool T, Biderre C, Delbac E, et al. Serodiagnostic studies in an immunocompetent individual infected with Encephalitozoon cuniculi. J Infect Dis 189(12):2243-2249, 2004.

Weber R, Deplazes P, Flepp M, et al. Cerebral microsporidiosis due to Encephalitozoon cuniculi in a patient with human immunodeficiency virus infection. N Engl J Med 337(7):474-478, 1997.

To cite this page:

Pollock C. Zoonotic concern: Encephalitozoonosis in European rabbits. August 18, 2011. LafeberVet Web site. Available at https://lafeber.com/vet/zoonotic-concern-encephalitozoonosis-in-european-rabbits/